(1) 肿瘤靶点相关的有机小分子药物设计、合成与作用机制研究
(2) 单分子尺度的表面化学反应可视化与低维有机量子材料的表面合成研究

截至2024/03，已发表SCI论文40余篇，其中以第一作者或通讯作者在Nat. Commun.、J. Am. Chem. Soc. (3篇)、Angew. Chem. Int. Ed.（4篇）等期刊上发表SCI论文30余篇；授权发明专利3项；主持国家和省部级科研项目8项。

1. Y. Wang, W.-W. Gong, Y. Zhao, G.-Y. Xing, L.-X. Kang, F. Sha, Z.-Y. Huang, J.-W. Liu, Y.-J. Han, P. Li, D.-Y. Li*, P.-N. Liu*. Two-Dimensional Nonbenzenoid Heteroacene Crystals Synthesized via In-Situ Embedding of Ladder Bipyrazinylenes on Au(111). Angew. Chem. Int. Ed. 2024, 63, e202318142.
2. J.-W. Liu, Y. Wang, L.-X. Kang, Y. Zhao, G.-Y. Xing, Z.-Y. Huang, Y.-C. Zhu, D.-Y. Li*, P.-N. Liu*. Two-dimensional crystal Transition from Radialene to Cumulene on Ag(111) via Retro-[2+1] Cycloaddition. J. Am. Chem. Soc. 2023, 145, 13048.
3. G. Zhu, Y. Jiang, Y. Wang, B.-X. Wang, Y. Zheng, Y. Liu, L.-X. Kang, Z. Li, D. Guan, Y. Li, H. Zheng, C. Liu, J. Jia, T. Lin, P.-N. Liu*, D.-Y. Li*, S. Wang*. Collective Quantum Magnetism in Nitrogen-Doped Nanographenes. J. Am. Chem. Soc. 2023. 145, 7136.
4. C. Li*, Y. Liu, Y. Liu, F.-H. Xue, D. Guan, Y. Li, H. Zheng, C. Liu, W. Luo, J. Jia, P.-N. Liu, D.-Y. Li*, S. Wang*. Topological Defects Induced High-Spin Quartet State in Truxene-Based Molecular Graphenoids. CCS Chem. 2023, 5, 695.
5. Y. Liu, C. Li*, F.-H. Xue, W. Su, Y. Wang, H. Huang, H. Yang, J. Chen, D. Guan, Y. Li, H. Zheng, C. Liu, M. Qin, X. Wang, R. Wang*, D.-Y. Li*, P.-N. Liu*, S. Wang*, J. Jia*. Quantum Phase Transition in Magnetic Nanographenes on a Lead Superconductor. Nano Lett. 2023, 23, 9704.
6. D.-Y. Li*, Y. Wang, X.-Y. Hou, Y.-T. Ren, L.-X. Kang, F.-H. Xue, Y.-C. Zhu, J.-W. Liu, M. Liu*, X.-Q. Shi*, X. Qiu*, P.-N. Liu*. On-Surface Synthesis of [3]Radialenes via [1+1+1] Cycloaddition. Angew. Chem. Int. Ed. 2022, 61, e202117714.
7. D.-Y. Li, X. Qiu, S.-W. Li, Y.-T. Ren, Y.-C. Zhu, C.-H. Shu, X.-Y. Hou, M. Liu*, X.-Q. Shi*, X. Qiu*, P.-N. Liu*. Ladder Phenylenes Synthesized on Au(111) Surface via Selective [2+2] Cycloaddition. J. Am. Chem. Soc. 2021, 143, 12955.
8. D.-Y. Li, Y.-C. Zhu, S.-W. Li, C.-H. Shu, P.-N. Liu*. Post-Functionalization of Supramolecular Polymers on Surface and the Chiral Assembly-Induced Enantioselective Reaction. Angew. Chem. Int. Ed. 2021, 60, 11370.
9. S.-W. Li, R.-X. Zhang, L.-X. Kang, D.-Y. Li*, Y.-L. Xie, C.-X. Wang, P.-N. Liu*. Steering Metal-Organic Network Structures through Conformations and Configurations on Surfaces. ACS Nano 2021, 15, 18014.
10. D.-Y. Li, S.-W. Li, Y.-L. Xie, X. Hua, Y.-T. Long, A. Wang, P.-N. Liu*. On-surface synthesis of planar dendrimers via divergent cross-coupling reaction. Nat. Commun. 2019, 10, 2414.

刘培念 教授团队