1、教育经历
(1) 2014/09-2019/07, 北京大学, 生命科学学院, 博士
(2) 2009/09-2014/07, 南京农业大学, 动物医学院, 学士
2、工作经历
(1) 2019/08-至今, 中国药科大学, 药学院, 特聘副研究员
3、学术荣誉
2020/10,江苏省双创博士
(1) 2014/09-2019/07, 北京大学, 生命科学学院, 博士
(2) 2009/09-2014/07, 南京农业大学, 动物医学院, 学士
2、工作经历
(1) 2019/08-至今, 中国药科大学, 药学院, 特聘副研究员
3、学术荣誉
2020/10,江苏省双创博士
(1) 新型生物传感器研究
(2) 智能药物递送系统及其生物医学应用
(3) 新分析技术开发
(2) 智能药物递送系统及其生物医学应用
(3) 新分析技术开发
1、科研项目
(1)国家自然科学基金委员会,青年项目,81703471,铁磁@超顺磁耦合空腔核壳FeCx@Fe3O4纳米结构增强肿瘤免疫治疗的研究,2021-01-01 至 2023-12-31,24万元,在研,主持
(2)江苏省科技厅,江苏省自然科学基金青年基金项目,BK20170740,多功能碳化铁纳米载体的可控制备及其增强肿瘤免疫治疗的研究,2020-07 至 2023-06,20万元,在研,主持
(3)科技部, 国家重点研发计划食品安全专项项目,2019YFC1605400,国际贸易重要食品的安全侦查与风险监控实验室应用示范,2019-12 至 2022-12,53.26万,在研,子课题主持
2、学术获奖
(1) 2018年8月,中国生物材料大会“青年学者奖”,排名第一
3、代表性科研成果
(1)发展新型侧向流动免疫层析技术用于疾病标志物、药物残留、食品等的现场快速检测,首次提出依靠共价键作用的非捕获抗体依赖型新策略,该策略与传统双抗夹心法相比,灵敏度能提高1000倍,此外还开发出多模式信号读出功能,进一步提高检测灵敏度,并且开发出检出线和质控线易于区分的双色读出线,并能实现针对临床病理样本的检测。
(2)发展新型金属基纳米药物,利用其生物相容性好、表面易修饰的特性实现主动靶向病变部位,利用类酶活性、光学性能、磁学性能等实现针对耐药致病性细菌和肿瘤细胞的高效治疗,并在细菌感染模型和肿瘤模型中取得优于临床药物的显著疗效。
(1)国家自然科学基金委员会,青年项目,81703471,铁磁@超顺磁耦合空腔核壳FeCx@Fe3O4纳米结构增强肿瘤免疫治疗的研究,2021-01-01 至 2023-12-31,24万元,在研,主持
(2)江苏省科技厅,江苏省自然科学基金青年基金项目,BK20170740,多功能碳化铁纳米载体的可控制备及其增强肿瘤免疫治疗的研究,2020-07 至 2023-06,20万元,在研,主持
(3)科技部, 国家重点研发计划食品安全专项项目,2019YFC1605400,国际贸易重要食品的安全侦查与风险监控实验室应用示范,2019-12 至 2022-12,53.26万,在研,子课题主持
2、学术获奖
(1) 2018年8月,中国生物材料大会“青年学者奖”,排名第一
3、代表性科研成果
(1)发展新型侧向流动免疫层析技术用于疾病标志物、药物残留、食品等的现场快速检测,首次提出依靠共价键作用的非捕获抗体依赖型新策略,该策略与传统双抗夹心法相比,灵敏度能提高1000倍,此外还开发出多模式信号读出功能,进一步提高检测灵敏度,并且开发出检出线和质控线易于区分的双色读出线,并能实现针对临床病理样本的检测。
(2)发展新型金属基纳米药物,利用其生物相容性好、表面易修饰的特性实现主动靶向病变部位,利用类酶活性、光学性能、磁学性能等实现针对耐药致病性细菌和肿瘤细胞的高效治疗,并在细菌感染模型和肿瘤模型中取得优于临床药物的显著疗效。
1. Ju et al. Protonated Charge Reversal Nanodrugs for Active Targeting Clearance of Helicobacter Pylori Accompanied by Gut Microbiota Protection, Advanced Functional Materials 2023, 2300682. (IF=19.0)
2. Ju et al. Multimodal Capture−antibody-independent Lateral Flow Immunoassay Based on AuNF−PMBA for Point-of-care Diagnosis of Bacterial Urinary Tract Infections, Chemical Engineering Journal 2023, 451, 11. (IF=15.1)
3. Ju et al. Recent Advances of Lateral Flow Immunoassay for Bacterial Detection: Capture-antibody-independent Strategies and High-sensitivity Detection Technologies, TrAC Trends in Analytical Chemistry 2023, 166, 117203. (IF=13.1)
4. Ju et al. Dual Signal Output Ratiometric Biosensor Platform with Regulable Nanofiber-mediated Signal Amplification Strategy for Ultrasensitive Detection of Tumor Biomarker, Chemical Engineering Journal 2023,469, 144026. (IF=15.1)
5. Ju et al. An Integrated Therapeutic and Preventive Nanozyme-Based Microneedle for Biofilm-Infected Diabetic Wound Healing, Advanced Healthcare Materials 2023. (IF=10.0)
6. Ju et al. A Fluorescent and Ratiometric Colorimetric Biosensor for Detection of Different Hazard Contaminants in Dairy Products, Sensors and Actuators B: Chemical 2023, 374, 9. (IF=8.4)
7. Ju et al. Personalized Demand-responsive Biphasic Microneedle Patch for Smart Drug Administration, Biomaterials Science 2023. (IF=6.6)
8. Ju et al. A Universal Boronate Affinity Capture-antibody-independent Lateral Flow Immunoassay for Point-of-care Glycoprotein Detection, Talanta 2023. (IF=6.1)
9. Ju et al. A Novel Methacryloyl Chitosan Hydrogel Microneedles Patch with Sustainable Drug Release Property for Effective Treatment of Psoriasis. Macromolecular Bioscience 2023. (IF=4.6)
10. Ju et al. A Universal Bacterial Catcher Au-PMBA-nanocrab-based Lateral Flow Immunoassay for Rapid Pathogens Detection, Analytical Chemistry 2022, 94, 4277. (IF=7.4)
11. Ju et al. A pH-responsive Biomimetic Drug Delivery Nanosystem for Targeted Chemo-photothermal Therapy of Tumors, Nano Research 2022, 15, 4274. (IF=9.9)
12. Ju et al. An Intrinsically Thermogenic Nanozyme for Synergistic Antibacterial Therapy, Biomaterials Science 2021, 9, 8323. (IF=7.59)
13. Ju et al. Gold Nanomaterial Engineering for Macrophage-Mediated Inflammation and Tumor Treatment. Advanced Healthcare Materials 2021, 10. (IF=9.93)
14. Ju et al. Near-infrared Light and Tumor Microenvironment Dual Responsive Size-switchable Nanocapsules for Multimodal Tumor Theranostics, Nature Communications 2019, 10, 4418. (IF=11.878)
15. Ju et al. Metal and Metal Oxide Nanomaterials for Fighting Planktonic Bacteria and Biofilms: A Review Emphasizing on Mechanistic Aspects, International Journal of Molecular Sciences 2022, 23, 22. (IF=5.6)
2. Ju et al. Multimodal Capture−antibody-independent Lateral Flow Immunoassay Based on AuNF−PMBA for Point-of-care Diagnosis of Bacterial Urinary Tract Infections, Chemical Engineering Journal 2023, 451, 11. (IF=15.1)
3. Ju et al. Recent Advances of Lateral Flow Immunoassay for Bacterial Detection: Capture-antibody-independent Strategies and High-sensitivity Detection Technologies, TrAC Trends in Analytical Chemistry 2023, 166, 117203. (IF=13.1)
4. Ju et al. Dual Signal Output Ratiometric Biosensor Platform with Regulable Nanofiber-mediated Signal Amplification Strategy for Ultrasensitive Detection of Tumor Biomarker, Chemical Engineering Journal 2023,469, 144026. (IF=15.1)
5. Ju et al. An Integrated Therapeutic and Preventive Nanozyme-Based Microneedle for Biofilm-Infected Diabetic Wound Healing, Advanced Healthcare Materials 2023. (IF=10.0)
6. Ju et al. A Fluorescent and Ratiometric Colorimetric Biosensor for Detection of Different Hazard Contaminants in Dairy Products, Sensors and Actuators B: Chemical 2023, 374, 9. (IF=8.4)
7. Ju et al. Personalized Demand-responsive Biphasic Microneedle Patch for Smart Drug Administration, Biomaterials Science 2023. (IF=6.6)
8. Ju et al. A Universal Boronate Affinity Capture-antibody-independent Lateral Flow Immunoassay for Point-of-care Glycoprotein Detection, Talanta 2023. (IF=6.1)
9. Ju et al. A Novel Methacryloyl Chitosan Hydrogel Microneedles Patch with Sustainable Drug Release Property for Effective Treatment of Psoriasis. Macromolecular Bioscience 2023. (IF=4.6)
10. Ju et al. A Universal Bacterial Catcher Au-PMBA-nanocrab-based Lateral Flow Immunoassay for Rapid Pathogens Detection, Analytical Chemistry 2022, 94, 4277. (IF=7.4)
11. Ju et al. A pH-responsive Biomimetic Drug Delivery Nanosystem for Targeted Chemo-photothermal Therapy of Tumors, Nano Research 2022, 15, 4274. (IF=9.9)
12. Ju et al. An Intrinsically Thermogenic Nanozyme for Synergistic Antibacterial Therapy, Biomaterials Science 2021, 9, 8323. (IF=7.59)
13. Ju et al. Gold Nanomaterial Engineering for Macrophage-Mediated Inflammation and Tumor Treatment. Advanced Healthcare Materials 2021, 10. (IF=9.93)
14. Ju et al. Near-infrared Light and Tumor Microenvironment Dual Responsive Size-switchable Nanocapsules for Multimodal Tumor Theranostics, Nature Communications 2019, 10, 4418. (IF=11.878)
15. Ju et al. Metal and Metal Oxide Nanomaterials for Fighting Planktonic Bacteria and Biofilms: A Review Emphasizing on Mechanistic Aspects, International Journal of Molecular Sciences 2022, 23, 22. (IF=5.6)
戴建君教授(团队负责人)
鞠艳敏副研究员
博士研究生
孙彩霞(2021级)
竺佳颖(2021级)
硕士研究生
刘聪(2020级)
代盼盼(2020级)
吴鹏程(2020级)
张士薄(2020级)
张启明(2020级)
左万超(2020级)
邓舒月(2020级)
周欣宇(2021级)
罗俊(2021级)
孟祥明(2021级)
戈兴(2021级)
鞠艳敏副研究员
博士研究生
孙彩霞(2021级)
竺佳颖(2021级)
硕士研究生
刘聪(2020级)
代盼盼(2020级)
吴鹏程(2020级)
张士薄(2020级)
张启明(2020级)
左万超(2020级)
邓舒月(2020级)
周欣宇(2021级)
罗俊(2021级)
孟祥明(2021级)
戈兴(2021级)